The Skeptics Guide to the Universe Forum

2023 Oscar nominations: How to watch all the major nominees - Los Angeles Times

QuoteHere's where to find nearly all of them. Be sure to watch this page, as we will update as more films get released for streaming.

Welcome to the 2023 Celebrity Death Pool.

Anyone can play, the more the merrier (or macabre-ier).

To play, copy the list below into a new post and rank the 50 celebrities in order from 1 to 50. With 1 being the most likely to die and 50 being the least likely.

Scoring will be (51-R). R= where the dead celebrity is ranked on your list.

The death of the top entry on your list would be worth 50 Points. The death of the bottom entry on your list would only be worth 1 point.

We will continue the WILD CARD. You can remove one name from the list and add your own celebrity in their place. Use this format:

xxxxxxx, xxxxx WILD CARD

(also note which celebrity was removed)

If your wild card wins you earn an additional 25 points (R+25).

Here's the new list in alphabetical order.

NOTE there are a few changes from last year's list in addition to the five new replacement entries


1    Akihito
2    Woody Allen
3    David Attenborough
4    Bob Barker
5    Harry Belafonte
6    Tony Bennett
7    Pete Best
8    Joe Biden
9    Stephen Breyer
10    Mel Brooks
11    Warren Buffett
12    Jimmy Carter
13    Raúl Castro
14    Dick Cheney
15    Petula Clark
16    Bill Clinton
17    Bill Cosby
18    Dalai Lama
19    Judi Dench
20    Clint Eastwood
21    Rudy Giuliani
22    Mick Jagger
23    Magic Johnson
24    Ted Kaczynski
25    Don King
26    Henry Kissinger
27    Norman Lear
28    June Lockhart
29    Paul McCartney
30    Mitch McConnell
31    George Miller
32    Rupert Murdoch
33    Elon Musk
34    Willie Nelson
35    Bob Newhart
36    Punsalmaagiin Ochirbat
37    Ozzy Osbourne
38    Roger Penrose
39    Pope Francis
40    Vladimir Putin
41    Robert Redford
42    Keith Richards
43    Eva Marie Saint
44    Maggie Smith
45    Ringo Starr
46    Clarence Thomas
47    Donald Trump
48    Dick Van Dyke
49    Brian Wilson
50    Volodymyr Zelenskyy

This topic is for listeners of the TWIV podcast. I'll post a link to each episode as it appears (or within a few days, if I'm late feel free post the link yourself).

Basically if you don't listen to an episode, don't participate in the discussions. Of course, that in no way implies or suggests that you can't be critical of TWIV, an episode, the hosts, etc. (There have been other topics here with similar limitations, and it is reasonable to limit discussion to those who have at least listened to the podcast episode being discussed.)
 
There may be only a couple of us who regularly listing to TWIV and this thread may not get any traction, but that's fine.

TWIV is my second favorite podcast, after SGU, and it's a close second. Imagine a podcast with five hosts, each the equivalent of , in terms of expertise in their fields.

Their fields are different aspects of virology, and they've been doing weekly podcasts since Sept., 2008.

Since the pandemic began they've put a lot of focus on SARS-CoV-2 virus and the COVID-19 disease, of course. And they added a weekly Clinical Update with Dr. Daniel Griffin Daniel O. Griffin

QuoteGriffin co-authored the textbook Parasitic Diseases (7th edition 2019). He is Senior Fellow in Infectious Disease at United Health Group, Instructor in Clinical Medicine, Columbia University Irving Medical Centre, and Infectious Disease Clinician Chief, Pro Health Care.

The podcast hosts:

Vincent Racaniello

Quote(January 2, 1953)  Higgins Professor in the Department of Microbiology and Immunology at Columbia University's College of Physicians and Surgeons. He is a co-author of a textbook on virology, Principles of Virology.

Rich Condit

QuoteUniversity of Florida:  Condit teaches virology to graduate students, medical students and undergraduate students.

Dickson Despommier

Quote(June 5, 1940) Emeritus professor of microbiology and Public Health at Columbia University. From 1971 to 2009, he conducted research on intracellular parasitism and taught courses on parasitic diseases, medical ecology and ecology.

Brianne Barker

QuoteDrew University: Associate Professor of Biology; Director of Undergraduate Research; Director of the Drew Summer Science Institute; Director of Specialized Honors and Associate Director of Baldwin Honors Program; Barker Lab

Alan Dove

QuoteFormer researcher, science journalist

Kathy Spindler

QuoteProfessor in the Department of Microbiology & Immunology at the University of Michigan; Spindler Lab

Wordle 257 3/6

🟦🟧⬜⬜⬜
🟧🟧🟧🟦⬜
🟧🟧🟧🟧🟧



Wordle - The New York Times

Quote
Guess the WORDLE in six tries.

Each guess must be a valid five-letter word. Hit the enter button to submit.

After each guess, the color of the tiles will change to show how close your guess was to the word.

Rank the 50 celebrities in order from 1 to 50. With 1 (Top) being the most likely to die and 50 (Bottom) being the least likely.

Scoring will be (51-R). Where R=where you ranked the celebrity.

Top of your list will be worth 50 Points. Bottom of your list will only be worth 1 point.

We will continue the WILD CARD. You can remove one name from the list and add your own celebrity in their place. Use this format:

xxxxxxx, xxxxx WILD CARD

If your wild card wins you earn an additional 25 points.

Here it is. It's probably Hollywood-centric, male-centric, anglo-centric.

1 Akihito December 23, 1933 (age 88)
2 Woody Allen November 30, 1935 (age 86)
3 David Attenborough May 8, 1926 (age 95)
4 Bob Barker December 12, 1923 (age 98)
5 Harry Belafonte March 1, 1927 (age 94)
6 Tony Bennett August 3, 1926 (age 95)
7 Pete Best 24 November 1941 (age 80)
8 Mel Brooks June 28, 1926 (age 95)
9 Stephen Breyer August 15, 1938 (age 83)
10 Jimmy Carter October 1, 1924 (age 97)
11 Raúl Castro June 3, 1931 (age 90)
12 Dick Cheney January 30, 1941 (age 80)
13 Petula Clark November 15, 1932 (age 89)
14 Bill Clinton August 19, 1946 (age 75)
15 Bill Cosby July 12, 1937 (age 84)
16 Judi Dench December 9, 1934 (age 87)
17 Lhamo Dhondup (14th Dalai Lama) July 6, 1935 (age 86)
18 Clint Eastwood May 31, 1930 (age 91)
19 Rudy Giuliani May 28, 1944 (age 77)
20 Mikhail Gorbachev March 2, 1931 (age 90)
21 Mick Jagger July 26, 1943 (age 78)
22 Magic Johnson August 14, 1959 (age 62)
23 Ted Kaczynski May 22, 1942 (age 79)
24 Don King August 20, 1931 (age 90)
25 Henry Kissinger May 27, 1923 (age 98)
26 Angela Lansbury October 16, 1925 (age 96)
27 Norman Lear July 27, 1922 (age 99)
28 Jerry Lee Lewis September 29, 1935 (age 86)
29 June Lockhart June 25, 1925 (age 96)
30 Paul McCartney June 18, 1942 (age 79)
31 Mitch McConnell February 20, 1942 (age 79)
32 George Miller March 3, 1945 (age 76)
33 Willie Nelson April 29, 1933 (age 88)
34 Bob Newhart September 5, 1929 (age 92)
35 Punsalmaagiin Ochirbat January 23, 1942 (age 79)
36 Yoko Ono February 18, 1933 (age 88)
37 Ozzy Osbourne December 3, 1948 (age 73)
38 Roger Penrose August 8, 1931 (age 90)
39 Robert Redford August 18, 1936 (age 85)
40 Keith Richards December18, 1943 (age 78)
41 Eva Marie Saint July 4, 1924 (age 97)
42 Maggie Smith December 28, 1934 (age 87)
43 Britney Spears December 2, 1981 (age 40)
44 Ringo Starr July 7, 1940 (age 81)
45 Donald Trump June 14, 1946 (age 75)
46 Dick Van Dyke December 13, 1925 (age 96)
47 Barbara Walters September 25, 1929 (age 92)
48 Brian Wilson June 20, 1942 (age 79)
49 Elizabeth II(Elizabeth Alexandra Mary Windsor) April 21, 1926 (age 95)
50 Steve Wozniak August 11, 1950 (age 71)

I'll post my picks shortly.

The Real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health a book by Robert F. Kennedy

Quote
Pharma-funded mainstream media has convinced millions of Americans that Dr. Anthony Fauci is a hero. He is anything but.
As director of the National Institute of Allergy and Infectious Diseases (NIAID), Dr. Anthony Fauci dispenses $6.1 billion in annual taxpayer-provided funding for scientific research, allowing him to dictate the subject, content, and outcome of scientific health research across the globe. Fauci uses the financial clout at his disposal to wield extraordinary influence over hospitals, universities, journals, and thousands of influential doctors and scientists--whose careers and institutions he has the power to ruin, advance, or reward.

During more than a year of painstaking and meticulous research, Robert F. Kennedy Jr. unearthed a shocking story that obliterates media spin on Dr. Fauci . . . and that will alarm every American--Democrat or Republican--who cares about democracy, our Constitution, and the future of our children's health.

The Real Anthony Fauci reveals how "America's Doctor" launched his career during the early AIDS crisis by partnering with pharmaceutical companies to sabotage safe and effective off-patent therapeutic treatments for AIDS. Fauci orchestrated fraudulent studies, and then pressured US Food and Drug Administration (FDA) regulators into approving a deadly chemotherapy treatment he had good reason to know was worthless against AIDS. Fauci repeatedly violated federal laws to allow his Pharma partners to use impoverished and dark-skinned children as lab rats in deadly experiments with toxic AIDS and cancer chemotherapies.

In early 2000, Fauci shook hands with Bill Gates in the library of Gates' $147 million Seattle mansion, cementing a partnership that would aim to control an increasingly profitable $60 billion global vaccine enterprise with unlimited growth potential. Through funding leverage and carefully cultivated personal relationships with heads of state and leading media and social media institutions, the Pharma-Fauci-Gates alliance exercises dominion over global health policy.

The Real Anthony Fauci details how Fauci, Gates, and their cohorts use their control of media outlets, scientific journals, key government and quasi-governmental agencies, global intelligence agencies, and influential scientists and physicians to flood the public with fearful propaganda about COVID-19 virulence and pathogenesis, and to muzzle debate and ruthlessly censor dissent.

This is not a joke. It's already a bestseller in California.

Quote from: jt512 on November 17, 2021, 05:54:08 AM

Quote from: gmalivuk on November 17, 2021, 05:11:19 AM

Quote from: CarbShark on November 16, 2021, 10:47:38 PM

Quote from: gmalivuk on November 16, 2021, 09:42:42 PM
So you're suggesting (with no evidence) that none of those symptomatic infections happened among people without comorbidities?

You're suggesting (with no evidence) that those symptomatic infections are happen among people without comorbidities.

You're making the much stronger claim. Do you have any evidence that the risk of symptomatic infection is at least 35x higher among people with comorbidities than without? Because that's what it would take for any reasonable chance for none of those infections to be among those without comorbidities.

Indeed, absence of comorbidities reduces your susceptibility to symptomatic infection by only about 24%.*

> 1 - ((4 + 76) / (1.189 + 1.197)) / ((4 + 86) / (1.025 + 1.025))
[1] 0.2362857

Or, to put it another way, if you have no comorbidities you are still 76% as likely to get a symptomatic COVID infection as someone with comorbidities.



*Computed from the "No comorbidity" and "Any comorbidity" lines from Table 10 here.

That's interesting, but they don't include obesity, overweight or age above 65 as comorbidities. Each of those are kind of a big deal.

I've been thinking about this lately.

Who are the top active science communicators today?

My list of top active science communicators
   Steve Novella (SGU)
   Cara Santa Maria (SGU)
   Lucy Jones (Cal Tech Geologist)
   Neil deGrasse Tyson
   Gary Taubes
   Daniel Griffin (TWIV)
   Vincent Racaniello (TWIV)
   
Honorable mentions
   Bill Nye
   Brian Dunning (Skeptoid)
   Rebecca Watson (formerly SGU)

And who are the greatest Science Communicators best of all time?

The Science Communicators Hall of Fame
   Carl Sagan
   Richard Feynman

Facebook and Wiki are down (for me and others).

Anyone else seeing issues? Other services are down too.

I miss wiki, not Facebook.

William Shatner will fly to space on Jeff Bezos' Blue Origin rocket

Quote
Captain Kirk is rocketing into space next week — boldly going where no other sci-fi actors have gone.
Jeff Bezos' space travel company, Blue Origin, announced Monday that "Star Trek" actor William Shatner will blast off from West Texas on Oct. 12.

"Yes, it's true; I'm going to be a 'rocket man!' " the 90-year-old tweeted. He added: "It's never too late to experience new things."

Bezos, the founder of Amazon, is a huge fan of the sci-fi series and even had a cameo as a high-ranking alien in the 2016 film "Star Trek Beyond." His rocket company invited Shatner to fly as its guest.
...
Shatner will become the oldest person to go to space. He'll join three others — two of them paying customers — aboard a Blue Origin capsule. He would have been the first actor in space if Russia weren't launching an actress and a film director to the International Space Station on Tuesday for almost two weeks of moviemaking.

This is another 3-hour podcast, and I haven't gone through the whole thing yet, but what I've heard so far is pretty good.



YANSS 213 – How to improve your chances of nudging the vaccine hesitant away from hesitancy and toward vaccination – You Are Not So Smart

Quote
In this episode of the You Are Not So Smart Podcast, we sit down with nine experts on communication, conversation, and persuasion to discuss the best methods for reaching out to the vaccine hesitant with the intention of nudging them away from hesitancy and toward vaccination.

The Nation Ignition Facility has finally achieved ignition, generating significantly more energy out than in.

Not sure why this isn't bigger news. The folks at Livermore are very excited.

Clapton was already a piece of work, but seriously? (Although it's hard not to like his music)

Eric Clapton takes a stand on venues requiring vaccination - Los Angeles Times

Quote
Eric Clapton is staying the course with his beliefs about the COVID-19 vaccines: He recently announced he won't be performing "where there is a discriminated audience present."

That means the guitar hero won't play concerts in venues that require ticket-holders to be vaccinated.

"Following the PM's announcement on Monday the 19th of July 2021 I feel honour bound to make an announcement of my own: I wish to say that I will not perform on any stage where there is a discriminated audience present," Clapton said in a statement released exclusively to Italian architect and vaccine skeptic Robin Monotti Graziadei, who posted it Tuesday on his Telegram feed and Wednesday on his unverified Instagram account.

2022 Ford F-150 Lightning First Look: The Electric Pickup Has a Shockingly Low Price, Mega Specs

Pricing starts about $40k.

Quote
The Lightning does not replace the "regular" F-150. It instead expands the truck family with a smoother, more aerodynamic electric version with cool lighting and wheels. It comes only with the four-door SuperCrew cab and a 5.5-foot bed. The look is distinct, with traces of Mustang Mach-E, but remains instantly recognizable as an F-150. Ford leadership told the truck's designers it didn't want the 2022 Lightning to look like a science experiment.

So it's a new version of the F-150, to go along with the Mach-E, which is the hybrid.

I'm a little disappointed with the range. (300 miles with the extended battery).

Now that vaccine is available, what are your experiences? The poll asks about your personal plans, but feel free to discuss others.

For example, my daughter is scheduled to get the Moderna vaccine on Thursday.  She's classified as a "medium risk health care worker." She's a child therapist.

New U.S. dietary guidelines: No added sugar for kids under 2 - Los Angeles Times

Quote
The new guidelines, released Tuesday, did not include two key recommendations made by scientists advising the government. Those advisers said in July that everyone should restrict their added sugar intake to less than 6% of daily calories and that men should limit their alcohol consumption to one drink per day.

Instead, the guidelines stick with previous advice: Keep added sugar below 10% of calories per day after age 2. And men should limit alcohol to no more than two drinks per day, twice as much as advised for women.

https://www.dietaryguidelines.gov/sites/default/files/2020-12/Dietary_Guidelines_for_Americans_2020-2025.pdf


They're still recommending 45-65% of calories from Carbs.

The guy who found the Forrest Fenn Treasure posted this video in June, 2019, nearly a year before he found it.

https://youtu.be/XFzM7Nn7_AY

Full disclosure: I searched for the treasure but was even in the same state where it had been hidden.

The first steps in the scientific method are to make an observation and develop a hypothesis.

I noticed something interesting and have developed a hypothesis.

But at this point the observation is merely an anecdote, so I'm wondering if anyone else would be interested in participating in an observation exercise.

Here's the observation:

My eyes always water whenever I'm slicing or chopping onions. I literally can't be in the kitchen. I've tried various strategies, including googles (helped a little), refrigerating the onions (no effect); under water (not practical).

But the other day I happened to be wearing my COVID-19 mask while I sliced a couple onions and no tears.

The next day I tried again with no goggles just the mask, and slicing three onions, finely chopping two, and no tears.

I tried slicing one more onion from the same batch without the mask and instantly my eyes started watering.

Here's the hypothesis:

Eye watering from slicing and chopping onions is more due to inhaling the moisture and chemicals released rather than the moisture and chemicals contacting the eyes, and stopping inhalation of the droples/aerosol is good way to avoid eyes watering while slicing onions.

Anyone else have watery eyes when slicing/chopping onions? Want to give this a try?


Here's the ask:

It's very simple, slice an onion or two wearing a mask and without wearing a mask, then answer these questions:

How much do your eyes water normally: (It's not bad; it's unpleasant; it's unbearable)

When you do both observations one after the other, start with the mask, then try without.

If you do it the other way around the aerosol/droplets will already be in your system. Ideally, do them after enough time to let the air clear and your body recover.

Results with mask:

What kind of mask did you wear? (Cloth; N-95; N-90; other)

How many onions did you work with?

What kind/size onions?

Did you slice, chop or both?

What is your technique? (Knife or device, any special methods)

Did your eyes water?

If yes:

How soon (in seconds) after you started did your eyes water?

How much did your eyes water? (It's not bad; it's unpleasant; it's unbearable)

Results without mask:

How many onions did you work with?

What kind/size onions?

Did you slice, chop or both?

What is your technique? (Knife or device, any special methods)

Did your eyes water?

If yes:

How soon (in seconds) after you started did your eyes water?

How much did your eyes water? (It's not bad; it's unpleasant; it's unbearable)



Any takers? Comments?

Would a topic for famous people who have tested positive be fun or morbid or both?

I'll start:

Virginia Governor Ralph Northam (D) and his wife.

This week temperatures are expected to be in the 100-110s F. Although our electric system is fairly stable, when we do have outages it's usually on the hottest days.

Normally, we're fine. But if power goes out now, I would have to go into the office (an hour drive each way) and risk exposure to COVID.

But now I'm thinking I could simply by a portable, gas-powered generator.

All I would need it for would be to keep the refrigerator running; the internet up; computer and laptops. A small window AC unit would be nice, so would a TV.

I'm thinking I could simply add up all the wattages of each of these devices and get a generator that would handle that.

Looks like I could do this for under $1000. This would also be helpful following earthquakes.

Anybody have experience with portable emergency generators?

Does this sound like a workable plan?

I had this thing here.

Quote from: CarbShark on August 05, 2020, 08:17:03 PM

I added a comment to that post but it didn't display.

When I tried to modify the post I could see it, but when I quoted the post it wasn't in the quote text.

I quoted my own post and added my comment and it displayed, but thought it was a good idea to report this to someone?

Here is what I posted:

There is a virus on, you know ;)

This morning we found out that the husband of a woman who volunteers with my wife in our Democratic club passed away.

So, for us that's two degrees of separation.

Also, early on, the weekend before the lockdown, we had a friend over for dinner. She was coughing a bit and thought she was having allergies.

She proceeded to get sick and her symptoms were consistent with a mild case. But she never got tested.

So that's one COVID death, with two degrees.

And possibly 1 degree with infection.

Anyone else?

This really isn't a game, I'm genuinely curious how close people are to cases of the virus.

Dr. Oz solicits Fox News viewers to join an at-home hydroxychloroquine clinical trial | Media Matters for America

Quote
Dr. Mehmet Oz used his now-daily Fox & Friends appearance to promote a "self-reported" hydroxychloroquine clinical trial from the University of Minnesota, claiming that  "they mail you the pills, you start the protocol, [and] tell them what happened." This comes as other hydroxychloroquine trials internationally have returned murky results so far or in some cases been canceled due to heart complications in patients.

WATCH THE CLIP HERE: https://www.mediamatters.org/coronavirus-covid-19/dr-oz-solicits-fox-news-viewers-join-home-hydroxychloroquine-clinical-trial

https://twitter.com/chrislongview/status/1242969490721210368

Joe Biden Coronavirus response ad.

Yes.

Monday 8 p.m. (Pacific Daylight Time, check local listings for time)

National Geographic Channel
Cosmos: Possible Worlds (cc) Ladder to the Stars (Season Premiere) An adventure spanning billions of years into the evolution of life. (s) (N)

After a lengthy hiatus, host Neil deGrasse Tyson returns with more dazzling out-of-this world trips through space and time as Season 3 opens with two new back-to-back episodes.

<a href="https://earthquake.usgs.gov/earthquakes/map/#%7B%22autoUpdate%22%3A%5B%22autoUpdate%22%5D%2C%22basemap%22%3A%22street%22%2C%22feed%22%3A%221day_m25%22%2C%22listFormat%22%3A%22default%22%2C%22mapposition%22%3A%5B%5B-29.075375179558346%2C627.5390624999999%5D%2C%5B32.65787573695528%2C657.421875%5D%5D%2C%22overlays%22%3A%5B%22plates%22%5D%2C%22restrictListToMap%22%3A%5B%22restrictListToMap%22%5D%2C%22search%22%3Anull%2C%22sort%22%3A%22newest%22%2C%22timezone%22%3A%22utc%22%2C%22viewModes%22%3A%5B%22map%22%2C%22list%22%5D%2C%22event%22%3Anull%7D">

Latest Earthquakes</a>

Quote
7.7
125km NNW of Lucea, Jamaica
2020-01-28 19:10:25 (UTC)

I didn't see a topic for these, and I think there should be one. The link is to the USGS Earthquake page which a lot of us in California have at the top of their browser bookmarks.

7.7 is big. If I were on any shore in with a direct line between me and the epicenter I'd head for higher ground.

Went to yesterday's show in downtown Los Angeles and was pleasantly surprised.

It was not at all what I expected. It was entertaining and funny and good to see the rogues in person.

The venue was packed, in the middle of the afternoon, and the crowd was very receptive and enthusiastically engaged.

If you listen regularly to the show and can make it to one of these I highly recommend it!

You may even bump into a fellow SGU forum poster, which was also fun!


Sent from my iPhone using Tapatalk

I'm in!

https://youtu.be/Emu0I2hNfUk

If you have a mac, this script may come in handy. 

In Safari, you can open a number of tabs to various articles or web pages you want to link to. The script will grab the title  and the URL of each, format them for a forum post, and display them in a dialog, where you have the option of sending them to your text editor or copying them to the clipboard so you can paste into a forum post. 

You also have the option of pasting in text that will appear as a quote.

This version requires TextWrangler to be installed on your system but it's easily modified to use BBEdit; Word or any other scriptable app, or none, in which case it would just send the text to the clipboard.

CAUTION: If you use this script you may be accused of doing Article Dumps.

To install this script copy and paste it into a new Script Editor document. Save that into the Safari Scripts folder to be accessible from your scripts menu (if that's not turned on you can activate it in the Script Editor preferences).

~/Library/Scripts/Applications/Safari

To use it open a document in Safari. Navigate to pages in any number of tabs. Select the script from the Scripts menu.

set headOpenTags to return
set headCloseTags to return

set linkOpenTag to return
set linkURLOpenTag to "<a href=\""
set linkURLCloseTagStart to "\">" & return
set linkURLCloseTagEnd to "</a>" & return

set linkCloseTag to return

tell application "Safari"
tell window 1
set AppleScript's text item delimiters to {}

set allTabs to every tab
set tabInfo to {}
repeat with x from 1 to count of tabs
tell tab x
set tabName to the name
set tabURL to URL
set ledeText to ""

set tabName to my ReplaceText(" - latimes.com", "", tabName)
set the end of tabInfo to {ledeText, linkOpenTag, linkURLOpenTag, tabURL, linkURLCloseTagStart, tabName, linkURLCloseTagEnd, linkCloseTag} as text
end tell
end repeat
end tell
end tell
set AppleScript's text item delimiters to {return}

set dialogPrompt to "Enter any quotes for this collection of links"

set dialogTitle to "Quotes for this collection of links"
set dialogAnswer to return & return
set userResponse to display dialog dialogPrompt ¬
default answer dialogAnswer ¬
buttons {"Okay", "Skip"} ¬
default button 1 ¬
with title dialogTitle ¬
giving up after 15
set {userText, userButton, userGaveUp} to {text returned of userResponse, button returned of userResponse, gave up of userResponse}

if not userGaveUp and userButton is "Okay" then
set textToQuote to userText
end if
if the (count of words of textToQuote) is not 0 then
set textToQuote to "[quote]" & return & textToQuote & return & "[/quote]" & return
end if

set textToQuote to ReplaceAllInText(return & return & "[/quote]", return & "[/quote]", textToQuote)
set textToQuote to ReplaceAllInText("[quote]" & return & return, "[quote]" & return, textToQuote)

set AppleScript's text item delimiters to {return}

set linkText to paragraphs of ({headOpenTags, headCloseTags, tabInfo, textToQuote} as text)
repeat
if item 1 of linkText is "" then
set linkText to the rest of linkText
else
exit repeat
end if
end repeat
set linkText to linkText as text
set linkText to ReplaceAllInText(return & return, return, linkText)

set dialogPrompt to "Copy links to clipboard or drop in new TextWrangler doc:" & return & return
set buttonsList to {"Cancel", "Copy", "TextWrangler"}
set userchoice to display dialog dialogPrompt ¬
default answer linkText ¬
buttons buttonsList ¬
default button ¬
"Copy" with title ¬
"Links" giving up after 90

set whichButton to button returned of userchoice
set linkText to text returned of userchoice




if whichButton is "TextWrangler" then
tell application "TextWrangler"
make new window at beginning
set text of window 1 to linkText
activate
end tell
else if whichButton is "Copy" then
tell application "Finder"

set the clipboard to linkText
end tell
end if

on ReplaceText(findString, replaceString, textToFix)
set AppleScript's text item delimiters to {findString}
set textToFix to every text item of textToFix
set AppleScript's text item delimiters to {replaceString}
set textToFix to textToFix as text
return textToFix
end ReplaceText
--ReplaceAllInText

on ReplaceAllInText(findString, replaceString, textToFix)
--findString: text or a list of text strings (all will be replaced)
--replaceString: texx or a list of text strings (only first will be used)
--textToFix: text
set saveTID to AppleScript's text item delimiters
repeat
set AppleScript's text item delimiters to findString as list
set textToFix to every text item of textToFix
if (count of textToFix) = 1 then
set textToFix to textToFix as text
exit repeat
end if
set AppleScript's text item delimiters to {replaceString}
set textToFix to textToFix as text
if replaceString is in {findString} then exit repeat -- exits after one pass to avoid infinite loop
end repeat
set AppleScript's text item delimiters to saveTID
return textToFix as text
end ReplaceAllInText


https://www.thefarside.com/


Yes, please.


Sent from my iPhone using Tapatalk

This is a topic that's important enough to me that I think it merits its own thread.

Based on the idea that cancer cells rely primarily and in some cases exclusively on glucose for energy (the Warburg effect) the idea of using carbohydrate restriction to fight cancer along with traditional methods (chemo; radiation; surgery) has gotten a lot of traction lately and shown significant promise.

But, there have not been enough studies to clearly show its effectiveness (or lack thereof) but there is very little or no evidence that it causes harm.

I have two close friends who have cancer now, one of them has known me since before I was a LCHF dieter, back when I was obese.

So I'm going to share this with him. He's fairly skeptical, and may dismiss it out of hand, but I would feel terrible if I did nothing, and then better studies start showing a beneficial effect while his cancer progresses. (He's doing chemo and after some progress his tumors have started growing again).

So here's what I found in a couple hours on pub med. I've read all the abstracts and will read the full text of as many as I can in the days to come.



EDIT: No new links here, just a quotes from a few of the articles.

<a href="https://www.ncbi.nlm.nih.gov/pubmed">

ketogenic diet and cancer - PubMed - NCBI</a>

Front Cell Dev Biol. 2019; 7: 80.
Published online 2019 May 15. doi: 10.3389/fcell.2019.00080
PMCID: PMC6530249
PMID: 31157222
Editorial: The Warburg Effect Regulation Under Siege: the Intertwined Pathways in Health and Disease
Concetta Bubici1,* and Salvatore Papa2,*

QuoteAs the implications of the Warburg effect in health and disease continue to emerge, we are entering into a renaissance period for metabolism research. Since the Warburg's original observation, we have learnt a lot about the effect of signal transduction on metabolic pathways and how cells rapidly reprogram their metabolism although much remains to be discovered.

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530249/">
Editorial: The Warburg Effect Regulation Under Siege: the Intertwined Pathways in Health and Disease</a>

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624453/">

Rationale, Feasibility and Acceptability of Ketogenic Diet for Cancer Treatment</a>


J Cancer Prev. 2017 Sep; 22(3): 127–134.
Published online 2017 Sep 30. doi: 10.15430/JCP.2017.22.3.127
PMCID: PMC5624453
PMID: 29018777
Rationale, Feasibility and Acceptability of Ketogenic Diet for Cancer Treatment
Hae-Yun Chung1 and Yoo Kyoung Park2

QuoteFrom this review, we found further evidence that ketogenic diet in cancer patients is safe and feasible as an adjuvant therapy. As described above, we could conclude that in order to see any significant progression or improvement by ketogenic diet, at least 3 to 4 weeks of ketogenic diet is required. Additionally, we suggest that not only body composition but also biomarker or measures for tumor size or tumor metabolism assessment is essential. We also conclude that the acceptability for ketone diet may be better in some cancer type (better in glioblastoma than gastric cancer).

<a href="https://www.ncbi.nlm.nih.gov/pubmed/28093985">

Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer. - PubMed - NCBI</a>

Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer
Author(s): Matteo Vergati, Eriseld Krasniqi, Girolamo D. Monte, Silvia Riondino, Doriana Vallone, Fiorella Guadagni, Patrizia Ferroni*, Mario Roselli.
Journal Name: Current Medicinal Chemistry
Volume 24 , Issue 12 , 2017

DOI : 10.2174/0929867324666170116122915

QuoteThe rationale of KD is valid both because it lowers carbohydrate uptake possibly leading to cancer cell starvation and apoptosis and, at the same time, increases the levels of ketone bodies available for energy production in normal cells but not in cancer cells which have an allegedly downregulated oxidative phosphorylation.

<a href="https://www.sciencedirect.com/science/article/pii/S2212877819304272?via%3Dihub">
Ketogenic diet in the treatment of cancer – Where do we stand? - ScienceDirect</a>
Molecular Metabolism
Review
Ketogenic diet in the treatment of cancer – Where do we stand?

Author links open overlay panelDaniela D.WeberSepidehAminzadeh-GohariJuliaTulipanLucaCatalanoRené G.FeichtingerBarbaraKofler

QuoteThe ketogenic diet probably creates an unfavorable metabolic environment for cancer cells and thus can be regarded as a promising adjuvant as a patient-specific multifactorial therapy. The majority of preclinical and several clinical studies argue for the use of the ketogenic diet in combination with standard therapies based on its potential to enhance the antitumor effects of classic chemo- and radiotherapy, its overall good safety and tolerability and increase in quality of life. However, to further elucidate the mechanisms of the ketogenic diet as a therapy and evaluate its application in clinical practice, more molecular studies as well as uniformly controlled clinical trials are needed.

<a href="https://www.ncbi.nlm.nih.gov/pubmed/31352797">
A Ketogenic Diet Is Acceptable in Women with Ovarian and Endometrial Cancer and Has No Adverse Effects on Blood Lipids: a Randomized, Controlled Tr... - PubMed - NCBI</a>
A Ketogenic Diet Is Acceptable in Women with Ovarian and Endometrial Cancer and Has No Adverse Effects on Blood Lipids: a Randomized, Controlled Trial.

Cohen CW1, Fontaine KR2, Arend RC3,4, Gower BA1.

QuoteAbstract
Ketogenic diets (KDs) are emerging as effective therapies for several chronic diseases, including cancer. However, concerns regarding safety and adherence may prevent clinicians from prescribing KDs. We hypothesized that a KD does not negatively affect blood lipid profile compared to a lower-fat diet in ovarian and endometrial cancer patients, and that KD subjects would demonstrate acceptable adherence. Subjects were randomized to either a KD (70% fat, 25% protein, 5% carbohydrate), or the American Cancer Society diet (ACS; high-fiber and lower-fat). Blood lipids and ketones were measured at baseline and after 12 weeks of the assigned intervention. Adherence measures included urinary ketones in the KD and 4 days' diet records. Diet records were also examined to identify general patterns of consumption. Differences between the diets on blood lipids and dietary intake were assessed with Analysis of covariance and independent t-tests. Correlation analyses were used to estimate associations between dietary intake and serum analytes. At 12 weeks, there were no significant differences between diet groups in blood lipids, after adjusting for baseline values and weight loss. Adherence among KD subjects ranged from 57% to 80%. These findings suggest that KDs may be a safe and achievable component of treatment for some cancer patients.

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544614/">
Wilhelm Brünings' forgotten contribution to the metabolic treatment of cancer utilizing hypoglycemia and a very low carbohydrate (ketogenic) diet</a>

QuoteFirst clinical pilot studies on the KD and cancer have been conducted,7,10, 11, 12, 13, 14 and several others are planned or currently running.15, 16, 17 These studies are based on mainly three rationales.18 First, KDs have been shown to be capable of slowing down tumor growth in many, although not all, animal models.18,19 Second, the replacement of carbohydrates with fat that is characteristic for a KD is supposed to account for the increased fat oxidation rates in cancer patients that are due to tumor-induced insulin resistance, in this way possibly protecting against skeletal muscle loss.20, 21, 22 Third, KDs are expected to sensitize tumor cells to radio- and chemotherapy, principally opening up a very broad range of applications as complementary cancer treatments. This at least partly relates to their ability to impair tumor cell glycolysis, reducing ATP levels and the ability to utilize substrates of glycolytic metabolism for protection against reactive oxygen species.23, 24, 25

<a href="https://www.ncbi.nlm.nih.gov/pubmed/30531479">
The emerging role of ketogenic diets in cancer treatment. - PubMed - NCBI</a>

Curr Opin Clin Nutr Metab Care. 2019 Mar;22(2):129-134. doi: 10.1097/MCO.0000000000000540.
The emerging role of ketogenic diets in cancer treatment.
Klement RJ1.
Author information
Department of Radiotherapy and Radiation Oncology, Leopoldina Hospital Schweinfurt, Schweinfurt, Germany.

Quote
Abstract
PURPOSE OF REVIEW:
Altered glucose metabolism in cancer cells is an almost ubiquitous observation, yet hardly exploited therapeutically. However, ketogenic diets have gained growing attention in recent years as a nontoxic broad-spectrum approach to target this major metabolic difference between normal and cancer cells. Although much research still needs to be done, new knowledge has been gained about the optimal utilization of ketogenic diets for cancer treatment that this review aims to summarize.
RECENT FINDINGS:
Although most preclinical studies indicate a therapeutic potential for ketogenic diets in cancer treatment, it is now becoming clear that not all tumors might respond positively. Early clinical trials have investigated ketogenic diets as a monotherapy and - while showing the safety of the approach even in advanced cancer patients - largely failed to prove survival prolonging effects. However, it gradually became clear that the greatest potential for ketogenic diets is as adjuvant treatments combined with pro-oxidative or targeted therapies initiated in early stages of the disease. Beneficial effects on body composition and quality of life have also been found.
SUMMARY:
Ketogenic diets against cancer are worth further exploration, both in the laboratory and clinically. Patients wishing to undertake a ketogenic diet during therapy should receive dietary counselling to avoid common mistakes and optimize compliance. Future research should focus more on important clinical endpoints.

<a href="https://www.cancernetwork.com/dietary-strategies-cancer">
Pros and Cons of Dietary Strategies Popular Among Cancer Patients | Cancer Network</a>

QuoteMore recently, however, preclinical research suggests that the potential mechanism of ketosis on cancer cells does not rely solely on the Warburg effect. The spectrum of altered growth, metabolism, and signaling metabolites incurred by ketosis may result in a cancer cell–specific induction of oxidative stress, thereby potentiating the effect of chemotherapy and radiation.[34,35] Additionally, ketogenic diets may have a protein-sparing effect that preserves lean body mass in the setting of cancer cachexia.[36] In animal models, ketogenic diets decrease the initiation, progression, and metastasis of cancer.[37]

Evidence in human clinical trials is limited to cases and small open-label studies, typically as salvage therapies, which confirm the feasibility and safety of ketogenic diets. These studies suggest that ketogenic diets are safe, and do not negatively impact quality of life. They are, however, difficult to adhere to, and many patients do not reach desired levels of ketones in the urine.[35,38-41] The bottom line is that ketogenic diets may have utility in certain individuals, especially in combination with other conventional therapies, but there is currently no reliable way to predict which patients might respond. They are exceedingly difficult to implement without professional dietary counseling. Moreover, poorly implemented ketogenic diets incur risk for micronutrient deficiency; are very high in saturated fat; are typically low in fiber; may include processed foods; and may exclude entire food groups, such as fruits, legumes, and many vegetables, which have been shown to be beneficial for cancer prevention and mortality (See Figure).

<a href="https://science.sciencemag.org/content/362/6416/764.long">
Dietary fat: From foe to friend? | Science</a>

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075178/">
Nutritional Targeting of Cancer Cell Metabolism in Obesity</a>

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834833/">
Investigating the Ketogenic Diet As Treatment for Primary Aggressive Brain Cancer: Challenges and Lessons Learned</a>

QuoteThere are both in vitro and in vivo animal studies to suggest that KD has the potential to augment the treatments currently available for patients with aggressive gliomas. The value of KD to treat humans with these malignancies has yet to be proven in clinical trials. There is currently a lack of standard KD protocols so that comparison of different trials is difficult. Rigorous diet management and objective measures of ketosis are required to fairly evaluate the effectiveness of the KD as therapy for aggressive gliomas.

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842847/">
Ketogenic diet in cancer therapy</a>

QuoteIn conclusion, clinical application of KDs as an adjuvant therapy for cancer patients first requires that the KD be evaluated for its anti-tumor effect for each single type/genetic subtype of cancer in a preclinical setting, as the safety and efficacy of the KD strongly depend on the tumor entity and its genotype. Based on the results of rigorous preclinical and clinical studies performed thus far, the KD would appear to be a promising and powerful option for adjuvant therapy for a range of cancers. Cancer-specific recommendations await the findings of randomized controlled clinical trials.

<a href="https://www.ncbi.nlm.nih.gov/pubmed/28924531">
Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Nega... - PubMed - NCBI</a>

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589510/">
Efficacy of Metabolically Supported Chemotherapy Combined with Ketogenic Diet, Hyperthermia, and Hyperbaric Oxygen Therapy for Stage IV Triple-Negative Breast Cancer</a>

<a href="https://www.ncbi.nlm.nih.gov/pubmed/28900345">
Alternative Ketogenic Diet with Coconut Milk in a Case with Underlying Colorectal Cancer. - PubMed - NCBI</a>

<a href="https://www.ncbi.nlm.nih.gov/pubmed/28455833">
Article on ketogenic dietary regimes for cancer highly misleading. - PubMed - NCBI</a>

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510645/">
Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung and Pancreatic Cancer: The University of Iowa Experience of Two Phase I Clinical Trials</a>

<a href="https://www.ncbi.nlm.nih.gov/pubmed/28366810">
A Nutritional Perspective of Ketogenic Diet in Cancer: A Narrative Review. - PubMed - NCBI</a>

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375425/">
Ketogenic Diets and Cancer: Emerging Evidence</a>

QuoteData from case reports and trials suggest KD use is safe and tolerable for patients with cancer. Although it would be ideal to conduct a larger trial using a randomized therapeutic approach, the current emphasis on drug-based trials is a formidable obstacle. Other major obstacles are patient initiative and adherence. For now, investigators must work with anecdotal data. Examination of gene expression patterns in mitochondria and mutations in ketolytic and glycolytic enzymes may prove useful in selecting potentially responsive patients. Combining this dietary approach with standard chemotherapeutic and radiotherapeutic options may help improve tumor response, and further research is desperately needed.

<a href="https://fivethirtyeight.com/features/significant-digits-for-thursday-aug-15-2019/">

Significant Digits For Thursday, Aug. 15, 2019 | FiveThirtyEight</a>

Quote
$12,049 in traffic fines
A computer hacker in California secured for himself as a cheeky joke the vanity license plate "NULL," a word often used in programing to indicate an empty or undefined value. As a result, he at one point faced $12,049 in traffic fines. Whenever a traffic cop in the state forgot to enter a license plate number along with a citation, it seems, the ticket got sent the hacker's way.

I just felt a 6.6 in the Mojave Desert.

First I heard some rattling around in the attic, sounded like a raccoon had gotten in.  That stopped, then a few seconds later it came back more intensely, all over the house, as if there were bears in the attic, and I felt the rolling motion, like standing on a surfboard in calm water. Lasted about 10 seconds. The first shaking was the P-waves and the second was the S-waves. The P-waves travel faster and are less intense. The S-waves move more slowly and are more intense.

This is the web page I go to whenever I feel something. But for one this size, it acts like a DOS attack as everyone tries to access the page at once.

<a href="https://earthquake.usgs.gov/earthquakes/map/#%7B%22autoUpdate%22%3A%5B%22autoUpdate%22%5D%2C%22basemap%22%3A%22street%22%2C%22feed%22%3A%221day_m25%22%2C%22listFormat%22%3A%22default%22%2C%22mapposition%22%3A%5B%5B29.6880527498568%2C589.02099609375%5D%2C%5B43.45291889355465%2C619.8706054687499%5D%5D%2C%22overlays%22%3A%5B%22plates%22%5D%2C%22restrictListToMap%22%3A%5B%22restrictListToMap%22%5D%2C%22search%22%3Anull%2C%22sort%22%3A%22newest%22%2C%22timezone%22%3A%22utc%22%2C%22viewModes%22%3A%5B%22map%22%2C%22list%22%5D%2C%22event%22%3A%22ci38443183%22%7D">
Latest Earthquakes</a>

Quote
M 6.4 - 12km SW of Searles Valley, CA

Time: 2019-07-04 17:33:48 (UTC) 10:33 (local time)
Location: 35.705°N 117.508°W
Depth: 8.7 km

I noticed that there were a few threads that mentioned earthquakes, but started this topic as a catch-all for earthquake reports and info.

<a href="https://www.latimes.com/entertainment/tv/la-et-st-game-of-thrones-greatest-tv-show-ever-20190411-story.html">

Is 'Game of Thrones' TV's greatest show of all time? Yes, it is - Los Angeles Times</a>

Quote
"What is the best show ever?' and the answer is easy: "Game of Thrones."
There are television series that more people have watched, that more people have loved, series that have more specifically aided our growth as a society, better showcased a single performance or more clearly set a template for other shows to follow.
But "Game of Thrones," adapted for HBO by D.B. Weiss and David Benioff from the book series by George R.R. Martin, is, and will possibly remain, the only television series that can be truly described as epic.
No other series has ever built such a deeply detailed and far-flung world, with a geography as varied as its social constructs, religions, languages. No other series has propelled such a massive yet impeccably individualized cast through such an impossibly intricate cat's cradle of story lines that honestly should have collapsed long ago but didn't.

https://g.co/doodle/3zrb48

QuoteReady to rock out with Bach? Today's #BachDoodle celebrates German composer and musician Johann Sebastian Bach with our very first AI-powered #GoogleDoodle → http://goo.gl/qJqcPB

<a href="https://www.latimes.com/local/california/la-me-ln-whooping-cough-harvard-20190226-story.html">

30 Harvard-Westlake students diagnosed with whooping cough amid wider outbreak - Los Angeles Times</a>

Quote
Thirty students at the private Harvard-Westlake School have recently fallen ill with whooping cough, part of a larger outbreak across Los Angeles County that officials are struggling to contain.

Harvard-Westlake is just as private and expensive as school as its name sounds. Most families sending kids there are millionaires.

I think yes

Take the Pro-Truth Pledge

QuoteTake the Pro-Truth Pledge to encourage politicians – and everyone else – to commit to truth-oriented behaviors and protect facts and civility. Join 9251 signers, 100 organizations, 643 government officials, and 966 public figures and take the pledge, demand that your elected representatives do so, and encourage your friends to take it!

Quote from: bachfiend on December 13, 2018, 10:18:33 PM

Quote from: gmalivuk on December 13, 2018, 07:47:19 PM

Quote from: bachfiend on December 13, 2018, 07:09:27 PM
I've provided a definition for 'imply' which has 'suggest' included

And I already explained that suggesting something is a logical consequence (which the definition said) is not the same as suggesting something is true (which you keep insisting).

QuoteAnd 'possible' and 'plausible' are synonyms.

Here, I'll let some folks explain it to you like you're five.

QuoteIf you want to continue this discussion on the meaning of words, then start a new thread.

Alternatively, if you don't want to continue it, then don't continue it...

Stay on topic.  Start a new thread if you want to continue your pointless quibbling about the mean of words (and it's not possible nor plausible that Clooney could be the next American President).

Redirecting a semantic discussion to its own thread.



Sent from my iPhone using Tapatalk

This just in:

Quote(New York) - Adam Savage will return to television as host and executive producer of MythBusters Jr., when the new Science Channel series premieres on Wednesday, January 2 at 9 p.m. ET/PT. For the ten-episode series Savage has teamed-up with six of the nation's leading young 'makers', robotics wizzes, builders, and inventors, all under the age of 16, who show off their amazing ingenuity and STEAM (Science, Technology, Engineering, Arts, and Math) skills.

I don't get the reference.

Interesting discussion about everyone's favorite or least favorite tycoon

https://feeds.publicradio.org/public_feeds/make-me-smart-with-kai-and-molly/itunes/rss

This discussion sprang from a thread on sweeteners.

My answers is yes.

But don't take my word for it.

The first step to arriving at an answer is to be clear on what criteria are used for addiction.

<a href="https://www.asam.org/resources/definition-of-addiction">
ASAM Definition of Addiction</a>

Quote
Short Definition of Addiction:
Addiction is a primary, chronic disease of brain reward, motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in an individual pathologically pursuing reward and/or relief by substance use and other behaviors.
Addiction is characterized by inability to consistently abstain, impairment in behavioral control, craving, diminished recognition of significant problems with one's behaviors and interpersonal relationships, and a dysfunctional emotional response. Like other chronic diseases, addiction often involves cycles of relapse and remission. Without treatment or engagement in recovery activities, addiction is progressive and can result in disability or premature death.

<a href="http://www.midss.org/content/yale-food-addiction-scale-yfas">
Yale Food Addiction Scale (YFAS) | Measurement Instrument Database for the Social Sciences</a>

The next step is to determine if Sugar, specifically, meets that criteria.

The final step is to determine if you, yourself, my be addicted to food. (Note, the food addition questionnaire applies to all foods, but if you take it limiting your answers to sweet and sugary foods, that should give you an answer.)

<a href="http://www.midss.org/sites/default/files/yale_food_addiction_scale.pdf">
‎www.midss.org/sites/default/files/yale_food_addiction_scale.pdf</a>

<a href="http://www.midss.org/sites/default/files/yfas_instruction_sheet.pdf">
‎www.midss.org/sites/default/files/yfas_instruction_sheet.pdf</a>

This thread is for mac owners and users to discuss Apple technology. It's purpose is not to engage in the Mac/PC/Unix debate. You can revive some long dead thread to bring that up, those conversations aren't welcome here (Just like the gun control threads, and diabetes thread). Of course, that doesn't mean only positive comments about Macs or Apple.

For my part my first computer was an Apple IIe, and have never owned any computer that wasn't an Apple. Although I work with Windows, Linux and proprietary Unix mainframe OS systems, my job mostly consists of work on a Mac, because it has features with no equivalent on any other system. (I still use HyperCard every day!)

Uh-oh.

<a href="http://www.latimes.com/nation/nationnow/la-na-hawaii-volcano-20180503-story.html">
Hawaii's famed Kilauea volcano erupts, spewing lava and forcing evacuations</a>

Quote
Hawaii's famed Kilauea volcano, which has been erupting continuously since 1983 and has long been a destination for tourists, underwent a new eruption Thursday that threatened neighborhoods with red-hot lava on the eastern edge of Hawaii Island, prompting evacuations.
A giant crack about 500 feet long formed directly in the lower-elevation neighborhood of Leilani Estates, which has a population of about 1,500. From the crack, lava was shooting like a fountain to heights of up to 100 feet — as if a garden hose filled with running water had been sliced along its length, said U.S. Geological Survey volcanologist Wendy Stovall, an expert on Kilauea.

This may not be a hoax...

New forensic analysis indicates bones were Amelia Earhart's -- ScienceDaily]

QuoteBone measurement analysis indicates that the remains found on a remote island in the South Pacific were likely those of legendary American pilot Amelia Earhart, according to a UT researcher.

Amelia Earhart and the Nikumaroro Bones: A 1941 Analysis versus Modern Quantitative Techniques | Jantz | Forensic Anthropology]

QuoteBone measurement analysis indicates that the remains found on a remote island in the South Pacific were likely those of legendary American pilot Amelia Earhart, according to a UT researcher.

Another thread was derailed by discussions of the USDA Dietary Guidelines and they come up so often I think they deserve their own topic.

One question is how many times have they been revised:

Answer 7

<a href="https://health.gov/dietaryguidelines/1980.asp">
1980 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/1985.asp">
1985 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/1990.asp">
1990 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/1995.asp">
1995 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/2000.asp">
2000 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/2005.asp">
2005 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/2010/">
2010 Dietary Guidelines - health.gov</a>

<a href="https://health.gov/dietaryguidelines/2015/">
2015–2020 Dietary Guidelines for Americans - health.gov</a>

Type II Diabetes was relatively rare until recently. Now it's reached epidemic proportions.

U.S. Diabetes Surveillance System

(Note, it's important to make the distinction between Type I and Type II. They are completely different conditions and have very little in common)

In my own family, my oldest sister reversed her TIID with bariatric surgery.

Another sister is on daily insulin injections with hers.

A sister-in-law has T2D that went unchecked for years and has numerous complications, including amputations, and is in a wheelchair. She had bariatric surgery and that helped but she did not go into full remission.

I was diagnosed as pre-diabetic 8 years ago, and have successfully avoided the disease.

Type II Diabetes is a progressive disease, and the current standard of care, using medication, exercise and moderate diet modification, only slow its progression.

There are only two treatments that have been found to lead to remission in a significant number of patients:

A low-carb ketogenic diet and bariatric surgery.

So here's some information to consider.

Pubmed advanced search for: (Type II diabetes) AND ketogenic diet 

(If you suspect I'm "cherry picking," do these searches yourself. I'd be happy to read any contradicted studies you find)

Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes ... - PubMed - NCBI

Quote
In a 12-month trial, adults with elevated HbA1c and body weight assigned to an LCK diet had greater reductions in HbA1c, lost more weight, and reduced more medications than those instructed to follow an MCCR diet.

Induced and controlled dietary ketosis as a regulator of obesity and metabolic syndrome pathologies. - PubMed - NCBI

Quote
The results demonstrated that the change over time from week 0 to week 10 was significant (p=0.001) in the ketogenic group for weight, body fat percentage, BMI, HgA1c and ketones. All variables for the ketogenic group out-performed those of the exercise and non-exercise groups, with five of the seven demonstrating statistical significance.

An Online Intervention Comparing a Very Low-Carbohydrate Ketogenic Diet and Lifestyle Recommendations Versus a Plate Method Diet in Overweight Individuals With Type 2 Diabetes: A Randomized Controlled Trial

Quote
Individuals with type 2 diabetes improved their glycemic control and lost more weight after being randomized to a very low-carbohydrate ketogenic diet and lifestyle online program rather than a conventional, low-fat diabetes diet online program. Thus, the online delivery of these very low-carbohydrate ketogenic diet and lifestyle recommendations may allow them to have a wider reach in the successful self-management of type 2 diabetes.

Short-term safety, tolerability and efficacy of a very low-calorie-ketogenic diet interventional weight loss program versus hypocaloric diet in patients with type 2 diabetes mellitus

Quote
The interventional weight loss program based on a VLCK diet is most effective in reducing body weight and improvement of glycemic control than a standard hypocaloric diet with safety and good tolerance for T2DM patients.

Low carbohydrate and ketogenic diets in type 2 diabetes : Current Opinion in Lipidology



Very low-carbohydrate ketogenic diet before bariatric surgery: prospective evaluation of a sequential diet. - PubMed - NCBI

Quote
OPOD, including 10 days of a VLCKD, was safe and effective in morbidly obese patients, and it seems to be promising in morbidly obese patients with and without T2DM scheduled for laparoscopic bariatric surgery.

Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes. - PubMed - NCBI

Quote
This study shows the beneficial effects of a ketogenic diet over the conventional LCD in obese diabetic subjects. The ketogenic diet appears to improve glycemic control. Therefore, diabetic patients on a ketogenic diet should be under strict medical supervision because the LCKD can significantly lower blood glucose levels.

Pubmed advance search for (Type II diabetes) AND bariatric surgery


Metabolic surgery for the treatment of type 2 diabetes in obese individuals. - PubMed - NCBI

Quote
Several bariatric operations originally designed to promote weight loss have been found to powerfully treat type 2 diabetes, causing remission in most cases, through diverse mechanisms additional to the secondary consequences of weight loss.

Three-year result of efficacy for type 2 diabetes mellitus control between laparoscopic duodenojejunal bypass compared with laparoscopic Roux-en-Y ... - PubMed - NCBI


Effect of bariatric surgery on diabetic nephropathy in obese type 2 diabetes patients in a retrospective 2-year study: A local pilot. - PubMed - NCBI

Quote
This study shows that bariatric surgery significantly improves diabetic nephropathy in obese type 2 diabetes mellitus subjects. The results suggest that in our local type 2 diabetes mellitus patients, it is possible not only to improve metabolic parameters, but also to reverse what may be considered established microvascular complications by means of bariatric surgery.

Recent advances in understanding/managing type 2 diabetes mellitus


Long-Term Outcomes of Three Types of Bariatric Surgery on Obesity and Type 2 Diabetes Control and Remission. - PubMed - NCBI

Quote
For all three surgeries, diabetes remission was higher than the baseline after 5 years; mean BMI and HbA1c decreased considerably during the first year postoperatively and remained lower than basal values throughout follow-up. Early improvements were greatest for RYGB, though the advantage over the other operations diminished with time.

Predictors of remission of diabetes mellitus in severely obese individuals undergoing bariatric surgery: do BMI or procedure choice matter? A meta-... - PubMed - NCBI

Quote
Bariatric surgery determines similar diabetes remission rates in patients with BMI of 35 kg/m2 or more or BMI of less than 35 kg/m2. Baseline BMI is unrelated to diabetes remission. The association of baseline waist circumference with glycated hemoglobin A1c reduction is likely due to selection bias. Bariatric or metabolic effects of the surgical procedures appear independent, and different indices are needed to predict them.

This thread is open to everyone and anyone. Any intelligent, thoughtful discussion relevant to the topic is welcome.

http://openargs.libsyn.com

OA139

Listening now....

She comes in around 22 mins.

This seems to be picking up steam, so maybe it's own thread?

Up first:Garrison Keillor

<a href="http://www.latimes.com/entertainment/la-et-entertainment-news-updates-garrison-keillor-says-he-has-been-fired-1511976974-htmlstory.html">
Garrison Keillor says he has been fired over alleged improper behavior - LA Times</a>

Quote
Garrison Keillor, the former host of "A Prairie Home Companion," said Wednesday he has been fired by Minnesota Public Radio over allegations of improper behavior.
Keillor told the Associated Press of his firing in an email. In a follow-up statement, he said he was fired over "a story that I think is more interesting and more complicated than the version MPR heard." He didn't give details of the allegations.